Recombinant Human FGF7 protein

Description :	KGF is a member of the family of fibroblast growth factors, it is secreted in large amounts by fibroblast-like stromal cells in epithelial tissues. The KGF receptor encodes a tyrosine kinase and is a member of the family of receptors binding aFGF and bFGF. Binding of KGF to its receptor is competed by aFGF and bFGF. Although KGF is a potent specific mitogen for many epithelial cells it is not so for fibroblasts and endothelial cells. KGF is thought to play an important role in the paracrine growth control of normal epithelial cells. KGF stimulates the proliferation of primary and secondary human keratinocytes to the same extent as EGF.
Source :	E. coli
Species :	Human
Form :	Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.0)
Molecular Mass :	19.0 kDa
Endotoxin :	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity :	95%
Applications :	Cell Assay
Storage :	The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade- 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Reconstitution :	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Tag :	Non

Gene Name	FGF7 fibroblast growth factor 7 [ Homo sapiens ]
Official Symbol	FGF7
Synonyms	FGF7; fibroblast growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); keratinocyte growth factor; KGF; FGF-7; heparin-binding growth factor 7; HBGF-7;
Gene ID	2252
mRNA Refseq	NM_002009
Protein Refseq	NP_002000
MIM	148180
UniProt ID	P21781
Chromosome Location	15q21.2
Pathway	Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; FGFR2b ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; Glypican 3 network, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem;
Function	chemoattractant activity; growth factor activity; heparin binding; type 2 fibroblast growth factor receptor binding;