Recombinant Human FABP2, GST-tagged

• Cat.No.: FABP2-12631H
• Product Overview: Recombinant Human FABP2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-132a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FABP2 fatty acid binding protein 2, intestinal [ Homo sapiens ]
• Official Symbol: FABP2
• Synonyms: FABP2; fatty acid binding protein 2, intestinal; fatty acid-binding protein, intestinal; I FABP; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; FABPI; I-FABP; MGC133132
• Gene ID: 2169
• mRNA Refseq: NM_000134
• Protein Refseq: NP_000125
• MIM: 134640
• UniProt ID: P12104
• Chromosome Location: 4q28-q31
• Pathway: Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem
• Function: fatty acid binding; long-chain fatty acid transporter activity; transporter activity