FABP2
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Official Full Name
fatty acid binding protein 2, intestinal -
Overview
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] -
Synonyms
FABP2;fatty acid binding protein 2, intestinal;FABPI;I-FABP;fatty acid-binding protein, intestinal;fatty acid-binding protein 2;intestinal-type fatty acid-binding protein
Recombinant Proteins
- Human
- Chicken
- Rat
- Cattle
- Mouse
- Pig
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- GST
- His
- Non
- His&T7
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
FABP2 involved in several pathways and played different roles in them. We selected most pathways FABP2 participated on our site, such as PPAR signaling pathway,Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with FABP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fat digestion and absorption | PNLIPRP1,AGPAT2,PPAP2B,DGAT2,PNLIP,PLA2G12A,PLA2G5,PPAP2A,APOA4,PLA2G2E |
| PPAR signaling pathway | ACADL,ACSL1A,PPARD,ADIPOQ,APOA5,GK2,ACSL5,ACAA1,FABP7B,CYP7A1A |
Protein Function
FABP2 has several biochemical functions, for example, fatty acid binding,protein binding,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FABP2 itself. We selected most functions FABP2 had, and list some proteins which have the same functions with FABP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | MIPB,AQP9A,ABCA4A,SLC51B,HIAT1A,SLC15A5,HIATL1,APODB,APODA.1,SYN1 |
| protein binding | THSD4,KLK4,MRPL48,FAM110C,NUAK1,ERAP1,TSKS,ABI2,KRT8,ADRB3 |
| fatty acid binding | PTGDS,FABP10A,FABP1A,GPR120,LBFABP,Alb,PMP2,CYP4A14,FABP7B,FABP1 |
Interacting Protein
FABP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FABP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FABP2.
AGR2;TERF2IP;ALDH1B1
Resources
Research Area
Lipid and Fatty Acid TransportEarly Endodermal Lineage Markers
Endodermal Lineage Markers
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References
