Recombinant Human ESRRG, GST-tagged

• Cat.No.: ESRRG-125H
• Product Overview: Recombinant Human GST-tagged Estrogen-related receptor gamma ligand-binding domain (ESRRG-LBD) consists of a 218 a.a. GST tag, a 15 a.a. flexible linker and a 224 a.a. ESRRG-LBD, Acc# NP_001429, amino acids 235-458, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: Estrogen-related receptor gamma (ERR-gamma or ESRRG) is also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3).
• Form: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.5 mM EDTA, 3 mM Dithiothreitol, 7 mM reduced glutathione, 20% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: ESRRG estrogen-related receptor gamma [ Homo sapiens ]
• Official Symbol: ESRRG
• Synonyms: ESRRG; estrogen-related receptor gamma; ERR gamma-2; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3; ERR3; NR3B3; ERRgamma; FLJ16023; KIAA0832; DKFZp781L1617
• Gene ID: 2104
• mRNA Refseq: NM_001134285
• Protein Refseq: NP_001127757
• MIM: 602969
• UniProt ID: P62508
• Chromosome Location: 1q41
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem
• Function: AF-2 domain binding; metal ion binding; receptor activity; retinoic acid receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding