Recombinant Human EPHA1

• Cat.No.: EPHA1-28577TH
• Product Overview: Recombinant fragment of Human Eph receptor A1 expressed in a Baculovirus infected Sf9 cell expression system with N-terminal proprietary tag, MWt 72kDa..

Specification

• Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
• Protein length: 408 amino acids
• Molecular Weight: 72.000kDa inclusive of tags
• Source: Baculovirus
• Biological activity: The Specific activity of EPHA1-28577TH was determined to be 28 nmol/min/mg.
• Form: Liquid
• Purity: Densitometry
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Tag: Non

Gene Information

• Gene Name: EPHA1 EPH receptor A1 [ Homo sapiens ]
• Official Symbol: EPHA1
• Synonyms: EPHA1; EPH receptor A1; EphA1 , EPHT, EPHT1; ephrin type-A receptor 1; EPH
• Gene ID: 2041
• mRNA Refseq: NM_005232
• Protein Refseq: NP_005223
• MIM: 179610
• Uniprot ID: P21709
• Chromosome Location: 7q32-q36
• Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHA forward signaling, organism-specific biosystem
• Function: ATP binding; nucleotide binding; protein kinase activity; protein kinase binding; receptor activity