Recombinant Human EOMES protein, His & GST-tagged

• Cat.No.: EOMES-1649H
• Product Overview: Recombinant Human EOMES aa. (Leu400~Ser669 (Accession # O95936)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 60.1kDa
• Protein length: Leu400~Ser669
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5

Gene Information

• Gene Name: EOMES eomesodermin [ Homo sapiens (human) ]
• Official Symbol: EOMES
• Synonyms: EOMES; eomesodermin; TBR2; eomesodermin homolog; T-box brain protein 2
• Gene ID: 8320
• mRNA Refseq: NM_001278182.1
• Protein Refseq: NP_001265111.1
• UniProt ID: O95936