Recombinant Human EMILIN1, His-tagged

• Cat.No.: EMILIN1-28554TH
• Product Overview: Recombinant fragment corresponding to amino acids 676-1016 of Human EMILIN1 with 6x His tag; 362 amino acids including tag, Predicted MWt 39.1 kDa .

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 341 amino acids
• Description: This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung.
• Conjugation: HIS
• Molecular Weight: 39.100kDa inclusive of tags
• Tissue specificity: Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver,
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 7.40Constituent:99% PBS
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 C1q domain.Contains 1 collagen-like domain.Contains 1 EMI domain.

Gene Information

• Gene Name: EMILIN1 elastin microfibril interfacer 1 [ Homo sapiens ]
• Official Symbol: EMILIN1
• Synonyms: EMILIN1; elastin microfibril interfacer 1; EMILIN-1; DKFZp586M121; gp115
• Gene ID: 11117
• mRNA Refseq: NM_007046
• Protein Refseq: NP_008977
• MIM: 130660
• Uniprot ID: Q9Y6C2
• Chromosome Location: 2p23.3-p23.2
• Function: extracellular matrix constituent conferring elasticity; identical protein binding; protein binding