Recombinant Full Length Human EMILIN1 Protein, GST-tagged

• Cat.No.: EMILIN1-4243HF
• Product Overview: Human EMILIN1 full-length ORF ( AAH07530, 1 a.a. - 347 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 63.91 kDa
• Protein length: 347 amino acids
• AA Sequence: MADLGATKDRIISEINRLQQEATEH ATESEGRFRGLEEGQAQAGQCPSLE GRLGRLEGVCERLDTVAGGLQGLRE GLSRHVAGLWAGLRETNTTSQMQAA LLEKLVGGQAGLGRRLGALNSSLQL LEDRLHQLSLKDLTGEGTKGPAGEA GPPGPPGLQGPPGPAGPPGSPGKDG QEGPIGPPGPQGEQGVEGAPAAPVP QVAFSAALSLPRSEPGTVPFDRVLL NDGGYYDPETGVFTAPLAGRYLLSA VLTGHRHEKVEAVLSRSNQGVARVD SGGYEPEGLEKKPVAESQPSPGTLG VFSLILPLQAGDTVCVDLVMGQLAH SEEPLTIFSGALLYGDPELEHA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EMILIN1 elastin microfibril interfacer 1 [ Homo sapiens ]
• Official Symbol: EMILIN1
• Synonyms: EMILIN1; elastin microfibril interfacer 1; EMILIN-1; DKFZp586M121; gp115; elastin microfibril interface located protein; elastin microfibril interface-located protein 1; EMI; EMILIN
• Gene ID: 11117
• mRNA Refseq: NM_007046
• Protein Refseq: NP_008977
• MIM: 130660
• UniProt ID: Q9Y6C2

Reviews

03/11/2023

The sensitivity and specificity of the EMILIN1 Protein have consistently delivered robust and consistent results, enhancing the efficiency and accuracy of my experimental workflows.

05/21/2019

It has consistently demonstrated high sensitivity and accuracy in detecting and quantifying target molecules, allowing for precise and reliable measurement of analytes in my experimental samples.

09/06/2018

Its versatility and reliability make it an excellent choice for research applications, and I highly recommend it to fellow scientists.

Q&As

Can EMILIN1 serve as a biomarker for neurological disorders?

Research is exploring the potential of EMILIN1 as a biomarker for certain neurological disorders, but further clinical validation is needed to establish its diagnostic utility.

Can EMILIN1 serve as a biomarker for lung diseases?

There is research interest in exploring the potential of EMILIN1 as a biomarker for lung diseases, particularly in the context of pulmonary fibrosis and related conditions.

How does EMILIN1 relate to skin disorders?

EMILIN1 is involved in the assembly and maintenance of elastic fibers in the skin, and its dysregulation has been implicated in skin disorders such as cutis laxa.

How does EMILIN1 relate to connective tissue disorders?

EMILIN1 is involved in maintaining the structural integrity of connective tissues, and its dysregulation has been linked to connective tissue disorders such as Marfan syndrome and Ehlers-Danlos syndrome.

What are the potential implications of EMILIN1 in neurological disorders?

EMILIN1 has been studied for its potential role in neurodevelopment and synaptic function, and its dysregulation may have implications for neurological disorders such as autism and schizophrenia.