EMILIN1
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Official Full Name
elastin microfibril interfacer 1 -
Overview
This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. -
Synonyms
EMILIN1;elastin microfibril interfacer 1;EMILIN-1;DKFZp586M121;gp115;Elastin microfibril interface located protein 1;Elastin microfibril interface located protein;Elastin microfibril interface-located protein 1;EMIL1_HUMAN;EMILIN 1;EMILIN;OTTHUMP00000122584;EMI
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Rat
- E. coli
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- N-His
- His
- GST
- His&GST
- Non
- His&Fc&Avi
Involved Pathway
EMILIN1 involved in several pathways and played different roles in them. We selected most pathways EMILIN1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EMILIN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
EMILIN1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMILIN1 itself. We selected most functions EMILIN1 had, and list some proteins which have the same functions with EMILIN1. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | GHRL,HRAS,SRRT,DHRS2,KIAA1274,ZBED1,TRIM29,HIF1AN,STEAP3,EMD |
Interacting Protein
EMILIN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMILIN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMILIN1.
MTMR9;PLAC9;IFT20;CTAGE5
Resources
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References
- Bot, S; Andreuzzi, E; et al. Multiple-interactions among EMILIN1 and EMILIN2 N- and C-terminal domains. MATRIX BIOLOGY 41:44-55(2015).
- Votteler, M; Berrio, DAC; et al. Elastogenesis at the onset of human cardiac valve development. DEVELOPMENT 140:2345-2353(2013).