Recombinant Human DYNLRB1, His-tagged

• Cat.No.: DYNLRB1-2750H
• Product Overview: Recombinant human DYNLRB1 human, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW =11.9 kDa (104aa) confirmed by MALDI-TOF.

Specification

• Cat. No.: DYNLRB1-2750H
• Description: Dynein light chain roadblock-type, also known as DYNLRB1 is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.
• Source: E.coli.
• Sequences Of Amino Acids: MAEVEETLKR LQSQKGVQGI IVVNTEGIPI KSTMDNPTTT QYASLMHSFI LKARSTVRDI DPQNDLTFLR IRSKKNEIMV APDKDYFLIV IQNPTELEHH HHHH
• Purity: > 95% by SDS – PAGE.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DYNLRB1 dynein, light chain, roadblock-type 1 [ Homo sapiens ]
• Synonyms: DYNLRB1; dynein, light chain, roadblock-type 1; BLP; BITH; DNCL2A; DNLC2A; ROBLD1; dynein light chain roadblock-type 1; Roadblock-1; ROBL/LC7-like 1; bithoraxoid-like protein; roadblock domain containing 1; dynein-associated protein Km23; dynein-associated protein HKM23; cytoplasmic dynein light chain 2A; dynein light chain 2A, cytoplasmic; roadblock domain-containing protein 1; dynein, cytoplasmic, light polypeptide 2A
• Gene ID: 83658
• mRNA Refseq: NM_014183
• Protein Refseq: NP_054902
• MIM: 607167
• UniProt ID: Q9NP97
• Chromosome Location: 20q11.21
• Function: microtubule motor activity; protein binding