Recombinant Human DTX2, GST-tagged

• Cat.No.: DTX2-12191H
• Product Overview: Recombinant Human DTX2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-253a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DTX2 deltex homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: DTX2
• Synonyms: DTX2; deltex homolog 2 (Drosophila); deltex (Drosophila) homolog 2; protein deltex-2; RNF58; hDTX2; deltex2; ring finger protein 58; zinc ion binding protein; KIAA1528; MGC71098
• Gene ID: 113878
• mRNA Refseq: NM_001102594
• Protein Refseq: NP_001096064
• MIM: 613141
• UniProt ID: Q86UW9
• Chromosome Location: 7q11.23
• Pathway: Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem
• Function: metal ion binding; protein binding; zinc ion binding