DTX2
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Official Full Name
deltex homolog 2 (Drosophila) -
Overview
DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)). -
Synonyms
DTX2;deltex homolog 2 (Drosophila);deltex (Drosophila) homolog 2;protein deltex-2;RNF58;Deltex 2;Deltex2;hDTX2;Highly similar to hPMSR6 [H.sapiens];Protein deltex 2;RING finger protein 58;Zinc ion binding protein
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
DTX2 involved in several pathways and played different roles in them. We selected most pathways DTX2 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus,Notch Signaling Pathway,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by NOTCH | MDKB,TLE3,MDKA,DNER,MDK,TLE2,TLE4,DLK1,RAB6A,HEYL |
| Notch signaling pathway | ADAM17A,ADAM17,HES1,HER15.1,DLK1,JAG1B,NOTCH1A,DTX1,NUMBL,RBPJB |
| Activated NOTCH1 Transmits Signal to the Nucleus | MIB1,ADAM10,JAG2,JAG1,DNER,CNTN1,DLK1 |
| Signal Transduction | ARHGAP26,RBP2A,ARHGAP32,RAB6A,PENK,PYGO1,RBP3,GPR31B,SST,TLE4 |
| Signaling by NOTCH1 | TLE3,DNER,DLK1,HEYL |
Protein Function
DTX2 has several biochemical functions, for example, ligase activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX2 itself. We selected most functions DTX2 had, and list some proteins which have the same functions with DTX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | KCNG4,TOPORS,CPS1,KCMF1,RNF149,TRIM62,TRIM58,CNOT4,RNF133,TRIM24 |
| zinc ion binding | TRIM72,ZDHHC9,SLC30A7,CTCF,IGHMBP2,CSRP1,BIRC2,MSRB3,UBR2,ERAP1 |
| protein binding | ARFRP1,NOP10,CELSR1,COMMD5,Car8,ENOX2,IL4R,KAT2B,SSTR2,ZNF622 |
Interacting Protein
DTX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX2.
UBE2D4;NCALD;NCS1;VSNL1
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References
- Garcia-Mendoza, E; Sanchez-Bravo, YA; et al. Lipophilic toxins in cultivated mussels (Mytilus galloprovincialis) from Baja California, Mexico. TOXICON 90:111-123(2014).
- Blanco, J; Arevalo, F; et al. Effect of the industrial steaming on the toxicity, estimated by LC-MS/MS, of mussels exposed for a long time to diarrhetic shellfish poisoning (DSP) toxins. FOOD CHEMISTRY 177:240-247(2015).
