Recombinant Human DIS3, His-tagged

• Cat.No.: DIS3-12004H
• Product Overview: Recombinant Human DIS3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 607-958a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DIS3 DIS3 mitotic control homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DIS3
• Synonyms: DIS3; DIS3 mitotic control homolog (S. cerevisiae); KIAA1008; exosome complex exonuclease RRP44; dis3p; EXOSC11; exosome component 11; RRP44; 2810028N01Rik; protein DIS3 homolog; ribosomal RNA-processing protein 44; mitotic control protein dis3 homolog; bA555G22.1; RP11-342J4.3; FLJ10484; MGC33035; DKFZp667L1817
• Gene ID: 22894
• mRNA Refseq: NM_001128226
• Protein Refseq: NP_001121698
• MIM: 607533
• UniProt ID: Q9Y2L1
• Chromosome Location: 13q21.32
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem
• Function: 3-5-exoribonuclease activity; RNA binding; endonuclease activity; exonuclease activity; guanyl-nucleotide exchange factor activity; hydrolase activity; protein binding; ribonuclease activity