Recombinant Human DEFA6 Protein, MYC/DDK-tagged

• Cat.No.: DEFA6-451H
• Product Overview: Recombinant Human DEFA6 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 8.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DEFA6 defensin, alpha 6, Paneth cell-specific [ Homo sapiens ]
• Official Symbol: DEFA6
• Synonyms: DEFA6; defensin, alpha 6, Paneth cell-specific; defensin-6; DEF6; HD 6; defensin 6; HD-6
• Gene ID: 1671
• mRNA Refseq: NM_001926
• Protein Refseq: NP_001917
• MIM: 600471
• UniProt ID: Q01524