Recombinant Human CYP26B1 Protein, GST-tagged

• Cat.No.: CYP26B1-2250H
• Product Overview: Human CYP26B1 full-length ORF ( NP_063938.1, 1 a.a. - 512 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Molecular Mass: 83.9 kDa
• AA Sequence: MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 [ Homo sapiens ]
• Official Symbol: CYP26B1
• Synonyms: CYP26B1; cytochrome P450, family 26, subfamily B, polypeptide 1; cytochrome P450 26B1; P450RAI 2; cytochrome P450 26A2; cytochrome P450RAI-2; cytochrome P450 CYP26B1 variant 2; retinoic acid-metabolizing cytochrome; cytochrome P450 retinoic acid-inactivating 2; cytochrome P450 retinoid metabolizing protein; RHFCA; CYP26A2; P450RAI2; P450RAI-2; MGC129613; DKFZp686G0638
• Gene ID: 56603
• mRNA Refseq: NM_019885
• Protein Refseq: NP_063938
• MIM: 605207
• UniProt ID: Q9NR63