Recombinant Human CX3CR1
Cat.No. : | CX3CR1-28062TH |
Product Overview : | Recombinant full length Human CX3CR1 protein with a proprietary tag; predicted mwt: 65.12 kDa. |
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Description : | Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. |
Protein length : | 355 amino acids |
Molecular Weight : | 65.120kDa |
Source : | Wheat germ |
Tissue specificity : | Expressed in lymphoid and neural tissues. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Reduced Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL |
Sequence Similarities : | Belongs to the G-protein coupled receptor 1 family. |
Tag : | Non |
Gene Name | CX3CR1 chemokine (C-X3-C motif) receptor 1 [ Homo sapiens ] |
Official Symbol | CX3CR1 |
Synonyms | CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28; |
Gene ID | 1524 |
mRNA Refseq | NM_001171171 |
Protein Refseq | NP_001164642 |
MIM | 601470 |
Uniprot ID | P49238 |
Chromosome Location | 3p21.3 |
Pathway | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function | C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; |
Not For Human Consumption!
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