Recombinant Human CRTC3 protein, His & T7-tagged

• Cat.No.: CRTC3-1114H
• Product Overview: Recombinant Human CRTC3 aa. (Met1~Phe103 (Accession # Q6UUV7) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Met1~Phe103
• Description: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.4kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 11.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CRTC3 CREB regulated transcription coactivator 3 [ Homo sapiens (human) ]
• Official Symbol: CRTC3
• Synonyms: CRTC3; CREB regulated transcription coactivator 3; TORC3; TORC-3; CREB-regulated transcription coactivator 3; transducer of regulated CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3
• Gene ID: 64784
• mRNA Refseq: NM_001042574.2
• Protein Refseq: NP_001036039.1
• UniProt ID: Q6UUV7