Recombinant Human CR1 Protein, His (Fc)-Avi-tagged

• Cat.No.: CR1-2727H
• Product Overview: Recombinant Human CR1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: CR1 complement component (3b/4b) receptor 1 (Knops blood group) [ Homo sapiens ]
• Official Symbol: CR1
• Synonyms: CR1; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3b/4b) receptor 1, including Knops blood group system; complement receptor type 1; CD35; KN; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component receptor 1; C3BR; C4BR
• Gene ID: 1378
• mRNA Refseq: NM_000573
• Protein Refseq: NP_000564
• MIM: 120620
• UniProt ID: P17927

Reviews

11/16/2021

The CR1 protein product received was as advertised, top quality and good value for money.

03/14/2021

The staff actively communicated with me and solved many technical problems.

10/19/2020

The technician gave me a thorough introduction to the CR1 protein so that I could understand its biochemical properties.

Q&As

What diseases is CR1 involved in?

CR1 is involved in the study of systemic lupus erythematosus and Alzheimer's disease.

Where is CR1 primarily expressed?

CR1 is predominantly expressed on peripheral blood cell membranes.

What biological processes is CR1 involved in?

CR1 plays a role in Aβ clearance, neuroinflammation, and taurine lesions.

What are the components of CR1?

CR1 consists of four major structural domains: 41aa signaling peptide, extracellular structural domain, 25aa transmembrane structural domain, and 43aa cytoplasmic structural domain.