Recombinant Human coxsackie virus and adenovirus receptor, His-tagged

• Cat.No.: CXADR-247H
• Product Overview: CXADR, 20-237aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 20-237 a.a.
• Description: CXADR is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. Recombinant human CXADR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
• Molecular Mass: 26 kDa (241aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSLSITTPE EMIEKAKGET AYLPCKFTLS PEDQGPLDIE WLISPADNQK VDQVIILYSG DKIYDDYYPD LKGRVHFTSN DLKSGDASIN VTNLQLSDIG TYQCKVKKAP GVANKKIHLV VLVKPSGARC YVDGSEEIGS DFKIKCEPKE GSLPLQYEWQ KLSDSQKMPT SWLAEMTSSV ISVKNASSEY SGTYSCTVRN RVGSDQCLLR LNVVPPSNKA G
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CXADR coxsackie virus and adenovirus receptor [ Homo sapiens ]
• Official Symbol: CXADR
• Synonyms: CXADR; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; CAR; HCVADR; CVB3-binding protein; coxsackievirus B-adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; HCAR; CAR4/6
• Gene ID: 1525
• mRNA Refseq: NM_001207063
• Protein Refseq: NP_001193992
• MIM: 602621
• UniProt ID: P78310
• Chromosome Location: 21q21.1
• Pathway: Adaptive Immune System, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Viral myocarditis, organism-specific biosystem
• Function: PDZ domain binding; beta-catenin binding; cell adhesion molecule binding; connexin binding; identical protein binding; protein binding; receptor activity; receptor binding