Recombinant Human COPS4, GST-tagged

• Cat.No.: COPS4-11461H
• Product Overview: Recombinant Human COPS4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-250a.a.
• Description: This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) [ Homo sapiens ]
• Official Symbol: COPS4
• Synonyms: COPS4; COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis); COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 4; COP9 signalosome complex subunit 4; CSN4; SGN4; signalosome subunit 4; JAB1-containing signalosome subunit 4; MGC10899; MGC15160
• Gene ID: 51138
• mRNA Refseq: NM_001258006
• Protein Refseq: NP_001244935
• UniProt ID: Q9BT78
• Chromosome Location: 4q21.22
• Function: protein binding