Recombinant Human COPS4 Protein, GST-tagged

• Cat.No.: COPS4-1704H
• Product Overview: Human COPS4 full-length ORF (BAG51250.1, 1 a.a. - 406 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
• Molecular Mass: 72.7 kDa
• AA Sequence: MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) [ Homo sapiens ]
• Official Symbol: COPS4
• Synonyms: COPS4; COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis); COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 4; COP9 signalosome complex subunit 4; CSN4; SGN4; signalosome subunit 4; JAB1-containing signalosome subunit 4; MGC10899; MGC15160
• Gene ID: 51138
• mRNA Refseq: NM_001258006
• Protein Refseq: NP_001244935
• MIM: 616008
• UniProt ID: Q9BT78