Recombinant Human COL1A1 protein(1021-1110 aa), C-His-tagged

• Cat.No.: COL1A1-2523H
• Product Overview: Recombinant Human COL1A1 protein(P02452)(1021-1110 aa), fused with C-terminal His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Protein length: 1021-1110 aa
• Form: 0.15 M Phosphate buffered saline
• Molecular Mass: 10.5 kDa
• AASequence: EGSPGRDGSPGAKGDRGETGPAGPP GAPGAPGAPGPVGPAGKSGDRGETG PAGPAGPVGPVGARGPAGPQGPRGD KGETGEQGDRGIKGH
• Storage: Shipped on dry ice. Avoid repeated freeze-thaw cycles. Upon receipt, 2 days when stored at 2 to 8 °C after thawing.
  Up to 12 months when aliquoted and stored at -20 to -80°C.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: COL1A1 collagen, type I, alpha 1 [ Homo sapiens ]
• Official Symbol: COL1A1
• Synonyms: COL1A1; collagen, type I, alpha 1; collagen alpha-1(I) chain; OI4; alpha-1 type I collagen; pro-alpha-1 collagen type 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain
• Gene ID: 1277
• mRNA Refseq: NM_000088
• Protein Refseq: NP_000079
• UniProt ID: P02452

Reviews

10/18/2022

Timely delivery, so I got the desired experimental results in the shortest possible time.

08/13/2022

Very good after-sales service, an excellent shopping experience!

03/15/2022

The product brochure is very detailed and has comprehensive basic information about the COL1A1 protein.

Q&As

What diseases is COL1A1 involved in?

COL1A1 has been associated with the study of colorectal, gastric and pancreatic cancers.

What are the effects of inhibiting COL1A1 expression?

Inhibition of COL1A1 expression can affect the expression of various genes, thereby inhibiting tumor cell proliferation and promoting cell apoptosis.

Where is COL1A1 mainly expressed?

COL1A1 is highly expressed in heart and muscle tissues.

What are the components of COL1A1?

COL1A1 consists of three conserved structural domains, Collagen, COLFI and VWC.

What are the biological functions of COL1A1?

COL1A1 is involved in maintaining tissue structure and angiogenesis.

How does COL1A1 expression change in colorectal cancer tissues?

COL1A1 expression is significantly upregulated in colorectal cancer tissues.