Recombinant Human COG8, GST-tagged

• Cat.No.: COG8-11422H
• Product Overview: Recombinant Human COG8 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.
• Protein length: C-term-219a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COG8 component of oligomeric golgi complex 8 [ Homo sapiens ]
• Official Symbol: COG8
• Synonyms: COG8; component of oligomeric golgi complex 8; conserved oligomeric Golgi complex subunit 8; DOR1; FLJ22315; dependent on RIC1; COG complex subunit 8; conserved oligomeric golgi complex component 8; CDG2H
• Gene ID: 84342
• mRNA Refseq: NM_032382
• Protein Refseq: NP_115758
• MIM: 606979
• UniProt ID: Q96MW5
• Chromosome Location: 16q22.1