Recombinant Human CGNL1, His-tagged

• Cat.No.: CGNL1-11150H
• Product Overview: Recombinant Human CGNL1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: C-term-350a.a.
• Description: This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CGNL1 cingulin-like 1 [ Homo sapiens ]
• Official Symbol: CGNL1
• Synonyms: Cgnl1; CGNL1_HUMAN; Cingulin like 1; Cingulin-like protein 1; FLJ14957; JACOP; Junction-associated coiled-coil protein; KIAA1749; MGC138254; Paracingulin
• Gene ID: 84952
• mRNA Refseq: NM_032866.4
• Protein Refseq: NP_116255.2
• MIM: 607856
• UniProt ID: Q0VF96
• Chromosome Location: 15q21.3
• Function: motor activity