Recombinant Human CEACAM21, His-tagged

• Cat.No.: CEACAM21-15898H
• Product Overview: Recombinant human CEACAM21 protein, fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Description: CEACAM21 is a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 25 kDa (229aa)
• Protein length: 35-240aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSWLFIASA PFEVAEGENV HLSVVYLPEN LYSYGWYKGK TVEPNQLIAA YVIDTHVRTP GPAYSGRETI SPSGDLHFQN VTLEDTGYYN LQVTYRNSQI EQASHHLRVY ESVAQPSIQA SSTTVTEKGS VVLTCHTNNT GTSFQWIFNN QRLQVTKRMK LSWFNHVLTI DPIRQEDAGE YQCEVSNPVS SNRSDPLKLT VKSDDNTLG
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 [ Homo sapiens ]
• Official Symbol: CEACAM21
• Synonyms: CEACAM21; carcinoembryonic antigen-related cell adhesion molecule 21; FLJ13540; R29124_1; CEACAM3; MGC119874
• Gene ID: 90273
• mRNA Refseq: NM_001098506
• Protein Refseq: NP_001091976
• UniProt ID: Q3KPI0
• Chromosome Location: 19q13.2