Recombinant Human CD4
Cat.No. : | CD4-27808TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 26-226 of Human CD4 |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Protein Length : | 26-226 a.a. |
Description : | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Gene Name | CD4 CD4 molecule [ Homo sapiens ] |
Official Symbol | CD4 |
Synonyms | CD4; CD4 molecule; CD4 antigen (p55); T-cell surface glycoprotein CD4; |
Gene ID | 920 |
mRNA Refseq | NM_000616 |
Protein Refseq | NP_000607 |
MIM | 186940 |
Uniprot ID | P01730 |
Chromosome Location | 12pter-p12 |
Pathway | Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Arf1 pathway, organism-specific biosystem; Binding and entry of HIV virion, organism-specific biosystem; |
Function | MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; |
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Not For Human Consumption!
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