Recombinant Human CD300C

• Cat.No.: CD300C-7729H
• Product Overview: Recombinant Human CD300C is produced with our mammalian cells expression system in HEK293. The target protein is expressed with sequence (Gly21Arg183) of Human CD300C.

Specification

• Description: CD300C is a singlepass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Iglike Vtype domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF35A) and CD300A (CMRF35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the crossregulation of TNF alpha and IFNalpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
• Source: HEK293 Cells
• Species: Human
• Form: Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2
• AA Sequence: GYFPLSHPMT VAGPVGGSLS VQCRYEKEHR TLNKFWCRPP QILRCDKIVE TKGSAGKRNG RVSIRDSPA NLSFTVTLEN LTEEDAGTYW CGVDTPWLRD FHDPIVEVEV SVFPAGTTTA S SPQSSMGT SGPPTKLPVH TWPSVTRKDS PEPSPHPGSL FSNVRVDHHH HHH*
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.
• Tag: Non

Gene Information

• Gene Name: CD300C CD300c molecule [ Homo sapiens ]
• Official Symbol: CD300C
• Synonyms: CD300C; CD300c molecule; CD300c antigen; CMRF35-like molecule 6; CMRF 35A; CMRF35; CMRF35A; IGSF16; LIR; CMRF35 antigen; CD300 antigen-like family member C; immunoglobulin superfamily member 16; CMRF35 leukocyte immunoglobulin-like receptor; CMRF35A leukocyte immunoglobulin-like receptor; CLM-6; CMRF-35; CMRF-35A; CMRF35A1; CMRF35-A1
• Gene ID: 10871
• mRNA Refseq: NM_006678
• Protein Refseq: NP_006669
• MIM: 606786
• UniProt ID: Q08708
• Chromosome Location: 17q25.2
• Function: receptor activity; transmembrane signaling receptor activity