CD300C
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Official Full Name
CD300c molecule -
Overview
The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes,;neutrophils, and some T and B lymphocytes (Jackson et al., 1992 (PubMed 1349532)). -
Synonyms
CD300C;CD300c molecule;CD300c antigen;CMRF35-like molecule 6;CMRF 35A;CMRF35;CMRF35A;IGSF16;LIR;CMRF35 antigen;CD300 antigen-like family member C;immunoglobulin superfamily member 16;CMRF35 leukocyte immunoglobulin-like receptor;CMRF35A leukocyte immunoglobulin-like receptor;CLM-6;CMRF-35;CMRF-35A;CMRF35A1;CMRF35-A1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Mus musculus
- HEK293
- Insect Cell
- CHO
- Wheat Germ
- Mammalian Cell
- E.coli
- Human Cell
- Mouse
- NS0
- In Vitro Cell Free System
- Mammalian cells
- E.coli expression system
- His
- Fc
- Non
- GST
- hIgG4
- His&T7
- His&Fc&Avi
Involved Pathway
CD300C involved in several pathways and played different roles in them. We selected most pathways CD300C participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD300C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | HCST,ASB13,SPSB2,RNF123,SIGLEC6,RNF111,CD200R3,LCP2A,RBCK1,MGC174152 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | LILRB5,KLRG1,CLEC2B,CD300LG,CD200R2,CD300LB,LILRA1,CD300LF,SIGLEC5,LILRB1 |
| Immune System | MAP3K8,LILRB4,CD200R4,BTR22,CD300LB,KLRB1A,STIM1B,C1rb,DHX9,ALCAMB |
Protein Function
CD300C has several biochemical functions, for example, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD300C itself. We selected most functions CD300C had, and list some proteins which have the same functions with CD300C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane signaling receptor activity | LGR6,Fzd4,OR2A4,OR4C12,FCAMR,LGR4,CD79A,NCR2,TNFRSF8,MARCO |
Interacting Protein
CD300C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD300C here. Most of them are supplied by our site. Hope this information will be useful for your research of CD300C.
MEST;MED20;GOPC
Resources
Research Area
ITIM/ITAM Immunoreceptors and Related MoleculesMacrophage Markers
Monocyte Markers
Dendritic Cell Activation
Dendritic Cell ITIM/ITAM Immunoreceptors
Related Services
Related Products
References
- Lankry, D; Rovis, TL; et al. The interaction between CD300a and phosphatidylserine inhibits tumor cell killing by NK cells. EUROPEAN JOURNAL OF IMMUNOLOGY 43:2151-2161(2013).
- Takahashi, M; Izawa, K; et al. Human CD300C Delivers an Fc Receptor-gamma-dependent Activating Signal in Mast Cells and Monocytes and Differs from CD300A in Ligand Recognition. JOURNAL OF BIOLOGICAL CHEMISTRY 288:7662-7675(2013).
