Recombinant Human CCNC, His-tagged

• Cat.No.: CCNC-27518TH
• Product Overview: Recombinant full length Cyclin C protein (Human) fused to a proprietary 16kDa tag, also with 6 x His tag at the very N-terminal end.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Tissue specificity: Highest levels in pancreas. High levels in heart, liver, skeletal muscle and kidney. Low levels in brain.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 0.5% Triton-X-100, 25mM HEPES, 125mM Potassium chloride, pH 7.9
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the cyclin family. Cyclin C subfamily.Contains 1 cyclin N-terminal domain.
• Full Length: Full L.

Gene Information

• Gene Name: CCNC cyclin C [ Homo sapiens ]
• Official Symbol: CCNC
• Synonyms: CCNC; cyclin C; cyclin-C; CycC
• Gene ID: 892
• mRNA Refseq: NM_001013399
• Protein Refseq: NP_001013417
• MIM: 123838
• Uniprot ID: P24863
• Chromosome Location: 6q21
• Pathway: Developmental Biology, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem
• Function: protein binding; protein kinase binding