CCNC

  • Official Full Name

    cyclin C

  • Overview

    The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    CCNC;cyclin C;cyclin-C;CycC;CCNC_HUMAN;hSRB11;OTTHUMP00000016897;SRB11 homolog

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
CCNC-10859H Recombinant Human CCNC, His-tagged E.coli Human His 1-283a.a.
CCNC-27518TH Recombinant Human CCNC, His-tagged E.coli Human His Full L.
CCNC-0657H Recombinant Human CCNC Protein, GST-Tagged Wheat Germ Human GST
CCNC-07H Recombinant Human Cyclin C E.coli Human Non 120-303 a.a.
CCNC-08H Recombinant Human CCNC, His tagged E.coli Human His 1-283 a.a.
CCNC-10317Z Recombinant Zebrafish CCNC Mammalian Cell Zebrafish His
CCNC-4033C Recombinant Chicken CCNC Mammalian Cell Chicken His
CCNC-823H Recombinant Human CCNC Protein, GST-His-tagged E.coli Human His&GST
CCNC-7714HCL Recombinant Human CCNC 293 Cell Lysate HEK293 Human Non
CCNC-7715HCL Recombinant Human CCNC 293 Cell Lysate HEK293 Human Non
CCNC-2965HF Recombinant Full Length Human CCNC Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 283 amino acids

    Involved Pathway

    CCNC involved in several pathways and played different roles in them. We selected most pathways CCNC participated on our site, such as Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,Constitutive Signaling by NOTCH1 PEST Domain Mutants,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression D1BWG0212E,EXOSC8,C2orf49,C7orf59,ZNF615,EIF1AX,CBX3A,HNRNPR,SF3A1,ZNF549
    Disease CDC37,HEY2,TNKS2,DERL2,OPN1SW,GPC6,LTF,KREMEN2,RBP1,TIRAP
    Constitutive Signaling by NOTCH1 PEST Domain Mutants JAG1,ADAM10,HEY1,CDK8,JAG2,MIB1,HDAC6,HDAC5,HEY2,HEYL
    Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants CDK8,JAG1,ADAM10,HDAC5,HEY1,HEY2,HEYL,JAG2,HDAC6,MIB1
    Developmental Biology EPHB4B,DOCK1,MYL9,FGF8B,POU5F3,LGI1A,RHOAE,MYOG,DUSP7,KALRNB
    Fatty acid, triacylglycerol, and ketone body metabolism APOA5,ACOT11B,MED23,MED31,MED21,G0S2,HELZ2,SREBF2,TMEM195,MED18
    Generic Transcription Pathway ESRRG,ZNF2,COX6C,ZNF544,ZIM2,PRDX2,NR6A1,ZNF10,ZNF697,KRBA1
    Diseases of signal transduction TRIM24,CDC37,HDAC5,OS9,KREMEN2,CDK8,DERL2,JAG2,TRAT1,OPN1MW2

    Protein Function

    CCNC has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase regulator activity,protein binding,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNC itself. We selected most functions CCNC had, and list some proteins which have the same functions with CCNC. You can find most of the proteins on our site.

    Function Related Protein
    protein binding MITF,NPM3,LDLRAP1,CPSF6,CDK13,PODXL2,BAD,MIA3,ATP7A,HEYL
    ubiquitin protein ligase activity TRIM3,STUB1,PPIL2,HECTD2,UBE2S,RNF152,PDZD4,ITCHA,UBE2Z,FANCL
    cyclin-dependent protein serine/threonine kinase regulator activity CCNE2,FAM58A,CCNL1A,CCNL1,CKS1B,CCNT2A,CKS2,CCNT1,PSTPIP2,CCNL1B

    Interacting Protein

    CCNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNC here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNC.

    CDK8

    Resources

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