Recombinant Human CCL18, 22-89 aa, His-tagged

• Cat.No.: CCL18-164H
• Product Overview: Recombinant human CCL18 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 10.4 kDa (93aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CCL18, also known as chemokine (C-C motif) ligand 18, a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes may be involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses.
• Form: Liquid. In 10mM Sodium Citrate pH3.5, 10% Glycerol.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method ).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Cytokine-cytokine receptor interaction

Gene Information

• Gene Name: CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) [ Homo sapiens ]
• Synonyms: CKb7; PARC; AMAC1; DCCK1; MIP-4; AMAC-1; DC-CK1; SCYA18; CCL18_HUMAN; C-C motif chemokine 18 [Precursor]; Small-inducible cytokine A18;Macrophage inflammatory protein 4; ulmonary and activation-regulated chemokine;CC chemokine PARC;Alternative macrophage activation-associated CC chemokine 1; Dendritic cell chemokine 1; CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
• Gene ID: 6362
• mRNA Refseq: NM_002988
• Protein Refseq: NP_002979
• MIM: 603757
• UniProt ID: P55774
• Chromosome Location: 17q11.2
• Function: chemokine activity