Recombinant Human CBFA2T3 Protein, MYC/DDK-tagged

Cat.No. : CBFA2T3-2730H
Product Overview : Recombinant Human CBFA2T3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Description : This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Source : HEK293
Species : Human
Tag : Myc&DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 71 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 [ Homo sapiens ]
Official Symbol CBFA2T3
Synonyms ETO2; MTG16; MTGR2; ZMYND4
Gene ID 863
mRNA Refseq NM_005187
Protein Refseq NP_005178
MIM 603870
UniProt ID O75081

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