Recombinant Human CBFA2T3 Protein, MYC/DDK-tagged
Cat.No. : | CBFA2T3-2730H |
Product Overview : | Recombinant Human CBFA2T3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
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Description : | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 71 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 [ Homo sapiens ] |
Official Symbol | CBFA2T3 |
Synonyms | ETO2; MTG16; MTGR2; ZMYND4 |
Gene ID | 863 |
mRNA Refseq | NM_005187 |
Protein Refseq | NP_005178 |
MIM | 603870 |
UniProt ID | O75081 |
Not For Human Consumption!
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