Recombinant Human BH3 Interacting Domain Death Agonist, His-tagged

• Cat.No.: BID-2427H
• Product Overview: Recombinant human truncated C-terminal Bid (aa 61-195) produced inE. coliis fused at the N-terminus to a His-tag.

Specification

• Cat. No.: BID-2427H
• Description: Bid is an abundant pro-apoptotic protein of the Bcl-2 family that is crucial for death receptor-mediated apoptosis in many cell systems. Bid action has been proposed to involve the mitochondrial re-location of its truncated from tBid, to facilitate the release of apoptogenic proteins like cytochrome c.
• Source/Host: E. coli.
• Concentration: 0.5mg/ml.
• Purity: ≥95% (SDS-PAGE). Affinity purified.
• Biological Activity: Facilitates Bax oligomerization and induces cytochrome c release in isolated mitochondria (10-50ng/ml).
• Application: Studies of Bid/Bax interaction and in vitro cytochrome c release.
• Formulation: Liquid. In PBS.
• Long Term Storage: -80°C.
• Protein length: 61-195 a.a.

Gene Information

• Gene Name: BID BH3 interacting domain death agonist [ Homo sapiens ]
• Synonyms: BID; BH3 interacting domain death agonist; FP497; MGC15319; MGC42355; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); OTTHUMP00000196197; desmocollin type 4; apoptic death agonist; Human BID coding sequence; BH3-interacting domain death agonist; p22 BID
• Gene ID: 637
• mRNA Refseq: NM_001196
• Protein Refseq: NP_001187
• MIM: 601997
• UniProt ID: P55957
• Chromosome Location: 22q11.1
• Pathway: Apoptosis; Natural killer cell mediated cytotoxicity; Apoptosis
• Function: death receptor binding; protein binding