Recombinant Human B2M & HLA-A protein(HPV16 E7)(YMLDLQPET), His-tagged

• Cat.No.: B2M & HLA-A-895H
• Product Overview: Recombinant Human HLA-A*0201 HPV16 E7 complex Protein is produced by our Mammalian expression system and the target gene encoding (YMLDLQPET)&Ile21-Met119&Gly25-Ile308 (Ala269Val) is expressed with a 10His tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• ProteinLength: (YMLDLQPET)&Ile21-Met119&Gly25-Ile308 (Ala269Val)
• Description: The HPV16 E7 protein plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. E7 protein has both transforming and trans-activating activities. It plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.
• Form: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4.
• Molecular Mass: 55-60kDa, reducing conditions.
• Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
  Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
  It is not recommended to reconstitute to a concentration less than 100μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: B2M beta-2-microglobulin [ Homo sapiens (human) ]
• Official Symbol: B2M; HLA-A
• Synonyms: B2M; HLA-A
• Gene ID: 567
• mRNA Refseq: NM_004048.4
• Protein Refseq: NP_004039.1
• MIM: 109700
• UniProt ID: P61769