Native Human Complement C4c

• Cat.No.: C4-195H

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: Complement C4 (C4) plays a central role in both the classical and lectin pathways of complement activation, with levels in human plasma ~0.4 mg/ml. C4 circulates in human plasma as a heterotrimer of 205,000 Da in plasma. The three disulfide-linked chains have molecular weights of 93 (alpha), 75 (beta), and 32 (gamma) kDa, although C4 is readily processed to smaller fragments (C4a, C4b, C4c), as evidenced by the molecular weight description below.
• Form: Frozen
• Bio-activity: Not biologically active
• Molecular Mass: 147000
• Purity: >= 85% by SDS-PAGE Reacts to C4 antisera on Western Blot
• Usage: For research use or for use in further manufacturing.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <= -70°c="" -="" avoid="">
• Storage Buffer: Phosphate Buffered Saline, pH 7.4