Recombinant Human ATOX1, GST-tagged
| Cat.No. : | ATOX1-9994H |
| Product Overview : | Recombinant Human ATOX1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 1-68a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name | ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ] |
| Official Symbol | ATOX1 |
| Synonyms | ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1 (antioxidant protein 1, yeast) homolog 1; copper transport protein ATOX1; HAH1; metal transport protein ATX1; ATX1; MGC138453; MGC138455; |
| Gene ID | 475 |
| mRNA Refseq | NM_004045 |
| Protein Refseq | NP_004036 |
| MIM | 602270 |
| UniProt ID | O00244 |
| Chromosome Location | 5q32 |
| Pathway | Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; |
| Function | copper chaperone activity; copper ion binding; copper-dependent protein binding; metal ion binding; metallochaperone activity; |
Not For Human Consumption!
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