Recombinant Human ASGR2 Protein, His-tagged

• Cat.No.: ASGR2-197H
• Product Overview: Recombinant Human ASGR2(Met1~Ala311) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 38.9kDa
• Protein length: Met1~Ala311
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: ASGR2 asialoglycoprotein receptor 2 [ Homo sapiens ]
• Official Symbol: ASGR2
• Synonyms: ASGR2; asialoglycoprotein receptor 2; CLEC4H2; hepatic lectin H2; HBxAg-binding protein; C-type lectin domain family 4 member H2; HL-2; HBXBP; ASGPR2; ASGP-R2; FLJ60040
• Gene ID: 433
• mRNA Refseq: NM_001181
• Protein Refseq: NP_001172
• MIM: 108361
• UniProt ID: P07307