Recombinant Human ASGR2, GST-tagged

• Cat.No.: ASGR2-9932H
• Product Overview: Recombinant Human ASGR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-287a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ASGR2 asialoglycoprotein receptor 2 [ Homo sapiens ]
• Official Symbol: ASGR2
• Synonyms: ASGR2; asialoglycoprotein receptor 2; CLEC4H2; hepatic lectin H2; HBxAg-binding protein; C-type lectin domain family 4 member H2; HL-2; HBXBP; ASGPR2; ASGP-R2; FLJ60040
• Gene ID: 433
• mRNA Refseq: NM_001181
• Protein Refseq: NP_001172
• MIM: 108361
• UniProt ID: P07307
• Chromosome Location: 17p
• Function: asialoglycoprotein receptor activity; protein binding; receptor activity; sugar binding