Recombinant Full Length Human ASGR2 Protein

• Cat.No.: ASGR2-30HF
• Product Overview: Recombinant full length Human Asialoglycoprotein Receptor 2, isoform 3 , with an N terminal proprietary tag; predicted MW 57.31 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 287 amino acids
• Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: Liquid
• Molecular Mass: 57.310kDa inclusive of tags
• AA Sequence: MAKDFQDIQQ LSSEENDHPF HQGPPPAQPL AQRLCSMVCF SLLALSFNIL LLVVICVTGS QSAQLQAELR SLKEAFSNFS SSTLTEVQAI STHGGSVGDK ITSLGAKLEK QQQDLKADHD ALLFHLKHFP VDLRFVACQM ELLHSNGSQR TCCPVNWVEH QGSCYWFSHS GKAWAEAEKY CQLENAHLVV INSWEEQRFI VQHTNPFNTW IGLTDSDGSW KWVDGTDYRH NYKNWAVTQP DNWRGHELGG SEDCVEVQPD GRWNDDFCLQ VYRWVCEKRR NATGEVA
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents: 0.3% Glutathione, 0.79% Tris HCl.

Gene Information

• Gene Name: ASGR2 asialoglycoprotein receptor 2 [ Homo sapiens ]
• Official Symbol: ASGR2
• Synonyms: ASGR2; asialoglycoprotein receptor 2; CLEC4H2
• Gene ID: 433
• mRNA Refseq: NM_001181
• Protein Refseq: NP_001172
• MIM: 108361
• UniProt ID: P07307