Recombinant Human Aprataxin, His-tagged
Cat.No. : | APTX-1935H |
Product Overview : | Recombinant Aprataxin protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques. 23.9kDa (205aa). |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. |
Purity : | > 95% by SDS – PAGE. |
Physical Appearance : | Liquid. |
Formulation : | Liquid. 20mM Tris-HCl buffer (pH7.5) containing 20% glycerol,100mM NaCl, 0.1mM PMSF. |
Concentration : | 0.25 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMQD PKM QVY KDEQ VVVIKDKYPK ARYHWLVLPW TSISSLKAVA REHLELLKHMHTVGEKVIVD FAGSSKLRFR LGYHAIPSMS HVHLHVISQD FDSPCLKNKK HWNSFNTEYF LE SQAVIEMV QEAGRVTVRD GMPELLKLPLRCHECQQ LLP SIPQ LKEHL R KH WT Q. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name | APTX aprataxin [ Homo sapiens ] |
Synonyms | APTX; aprataxin; AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT; MGC1072; FLJ20157; forkhead-associated domain histidine triad-like protein; ataxia 1, early onset with hypoalbuminemia |
Gene ID | 54840 |
mRNA Refseq | NM_017692 |
Protein Refseq | NP_060162 |
MIM | 606350 |
UniProt ID | Q7Z2E3 |
Chromosome Location | 9p13.3 |
Function | DNA 5"-adenosine monophosphate hydrolase activity;chromatin binding;damaged DNA binding;double-stranded DNA binding;double-stranded RNA binding;hydrolase activity;metal ion binding;phosphoglycolate phosphatase activity;protein N-terminus binding;protein binding;zinc ion binding |
◆ Recombinant Proteins | ||
APTX-1212HF | Recombinant Full Length Human APTX Protein, GST-tagged | +Inquiry |
APTX-1935H | Recombinant Human Aprataxin, His-tagged | +Inquiry |
APTX-1540H | Recombinant Human APTX protein | +Inquiry |
APTX-390R | Recombinant Rat APTX Protein, His (Fc)-Avi-tagged | +Inquiry |
APTX-731H | Recombinant Human APTX protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
APTX-103HCL | Recombinant Human APTX cell lysate | +Inquiry |
Not For Human Consumption!
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