Recombinant Full Length Human APTX Protein, GST-tagged

• Cat.No.: APTX-1212HF
• Product Overview: Human APTX full-length ORF ( NP_778242.1, 1 a.a. - 254 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 254 amino acids
• Description: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]
• Molecular Mass: 55.5 kDa
• AA Sequence: MVNELYPYIV EFEEEAKNPG LETHRKRKRS GNSDSIERDA AQEAEAGTGL EPGSNSGQCS VPLKKGKDAP IKKESLGHWS QGLKISMQDP KMQVYKDEQV VVIKDKYPKA RYHWLVLPWT SISSLKAVAR EHLELLKHMH TVGEKVIVDF AGSSKLRFRL GYHAIPSMSH VHLHVISQDF DSPCLKNKKH WNSFNTEYFL ESQAVIEMVQ EAGRVTVRDG MPELLKLPLR CHECQQLLPS IPQLKEHLRK HWTQ
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: APTX aprataxin [ Homo sapiens (human) ]
• Official Symbol: APTX
• Synonyms: APTX; aprataxin; AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT; forkhead-associated domain histidine triad-like protein
• Gene ID: 54840
• mRNA Refseq: NM_001195248
• Protein Refseq: NP_001182177
• MIM: 606350
• UniProt ID: Q7Z2E3