Recombinant Human APTX protein, T7-tagged

• Cat.No.: APTX-258H
• Product Overview: Recombinant Human APTX fused with T7 tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
• Source: E. coli
• Species: Human
• Tag: T7
• Form: Supplied as a liquid in PBS, pH 7.2. No preservative added.
• Applications: ELISA (EL/EIA). Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard.
• Notes: Small volumes of Aprataxin recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Stability: May be stored at 4 centigrade for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 centigrade. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
• Storage: Storage at -70 centigrade

Gene Information

• Gene Name: APTX aprataxin [ Homo sapiens ]
• Official Symbol: APTX
• Synonyms: AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT; aprataxin; forkhead-associated domain histidine triad-like protein
• Gene ID: 54840
• mRNA Refseq: NM_001195248
• Protein Refseq: NP_001182177
• MIM: 606350
• UniProt ID: Q7Z2E3
• Chromosome Location: 9p13.3
• Function: DNA 5'-adenosine monophosphate hydrolase activity; chromatin binding; damaged DNA binding