Recombinant Human ANKHD1, His-tagged

• Cat.No.: ANKHD1-9659H
• Product Overview: Recombinant Human ANKHD1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ANKHD1 ankyrin repeat and KH domain containing 1 [ Homo sapiens ]
• Official Symbol: ANKHD1
• Synonyms: ANKHD1; ankyrin repeat and KH domain containing 1; ankyrin repeat and KH domain-containing protein 1; FLJ10042; FLJ11979; FLJ14127; FLJ20288; KIAA1085; MASK; HIV-1 Vpr-binding ankyrin repeat protein; multiple ankyrin repeats, single KH-domain homolog; VBARP; PP2500
• Gene ID: 54882
• mRNA Refseq: NM_001197030
• Protein Refseq: NP_001183959
• MIM: 610500
• UniProt ID: Q8IWZ3
• Chromosome Location: 5q31.3
• Function: RNA binding; protein binding