Recombinant Human ANKHD1 Protein, MYC/DDK-tagged

• Cat.No.: ANKHD1-2073H
• Product Overview: Recombinant human ANKHD1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 64.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ANKHD1 ankyrin repeat and KH domain containing 1 [ Homo sapiens ]
• Official Symbol: ANKHD1
• Synonyms: MASK; MASK1; PP2500; VBARP
• Gene ID: 54882
• mRNA Refseq: NM_001197030
• Protein Refseq: NP_001183959
• MIM: 610500
• UniProt ID: Q8IWZ3