Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged

• Cat.No.: ARL6-4974H
• Product Overview: Recombinant humanARL6 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Cat. No.: ARL6-4974H
• Description: ARL6, also knownADP-ribosylation factor-like protein 6, belongs to the ARF family ofGTP-binding proteins. This protein is known to play essential roles inmodulating membrane trafficking and cytoskeletal functions. Mutation in ARL6causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disordercharacterized by obesity, photoreceptor degeneration, polydactyly,hypogenitalism, renal abnor-malities and developmental delay.
• Concentration: 0.5 mg/ml
• Source: Human
• Host: E. coli
• Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.2 M NaCl and 5mM DTT.
• Purity: > 90% by SDS-PAGE
• Sequence: 1-186 amino acids:MGSSHHHHHH SSGLVPRGSH MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPTIGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKHRRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT
• Molecular Mass: 23.2 kDa (206 aa),confirmed by MALDI-TOF
• Applications: SDS-PAGE
• Storage: Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: ARL6

Gene Information

• Gene Name: ARL6 ADP-ribosylation factor-like 6 [ Homosapiens ]
• Synonyms: ARL6;ADP-ribosylation factor-like 6; BBS3; RP55; MGC32934; Bardet-Biedl syndrome 3protein; OTTHUMP00000214308; OTTHUMP00000214309; OTTHUMP00000214310;ADP-ribosylation factor-like protein 6
• Gene ID: 84100
• mRNA Refseq: NM_032146
• Protein Refseq: NP_115522
• MIM: 608845
• UniProt ID: Q9H0F7
• Chromosome Location: 3q11.2
• Function: GTP binding; metalion binding; nucleotide binding; phospholipid binding