Recombinant Human ARL6, His-tagged

• Cat.No.: ARL6-26185TH
• Product Overview: Recombinant full length Human ARL6 with an N terminal His tag; 206 amino acids with the tag; predicted MWt: 23.2 kDa.

Specification

• Description: The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.
• Protein length: 186 amino acids
• Conjugation: HIS
• Molecular Weight: 23.200kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPT IGFSIEKFKS SSLSFTVFDM ASDAIKGEGL QEGVDWLQDQ IQTVKT
• Sequence Similarities: Belongs to the small GTPase superfamily. Arf family.

Gene Information

• Gene Name: ARL6 ADP-ribosylation factor-like 6 [ Homo sapiens ]
• Official Symbol: ARL6
• Synonyms: ARL6; ADP-ribosylation factor-like 6; BBS3; ADP-ribosylation factor-like protein 6
• Gene ID: 84100
• mRNA Refseq: NM_177976
• Protein Refseq: NP_816931
• MIM: 608845
• Uniprot ID: Q9H0F7
• Chromosome Location: 3q11.2
• Function: GTP binding; metal ion binding; nucleotide binding; phospholipid binding