Recombinant Human ADIPOQ, Globular Domain, His-tagged

• Cat.No.: ADIPOQ-42H
• Product Overview: Recombinant Human globular domain of Adiponectin has total 171 amino acids. N-terminal underlined amino acids are His-tag and the protease cleavage site (31AA-Underlined). The AA sequence is homologous to the 105-244 amino acid sequence of the Human full-length Adiponectin.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 105-244 a.a.
• Description: Adiponectin is a protein exclusively secreted from adipose tissue. In the circulation, adiponectin is present as three different oligomeric complexes, including the high molecular weight (HMW), the middle molecular weight (MMW, also called hexamer) and low molecular weigh (LMW, also called trimer) forms. Different oligomeric complex of adiponectin activates different signaling pathways and exerts distinct functions.
• Amino Acid Sequence: MSWWHHHHHH NWNIPTTQDT TQDLWFEGAM GGEGAYVYRS FSVGLETYV TIPNMPIRFT KIFYNQQNHYDGSTGKFHCN IPGLYYFAYH ITVYMKDVKV SLFKKDKAML FTYDQYQENN VDQASGSVLL HEVGDQVWLQVYGEGERNGL YADNDNDSTF TGFLLYHDTN.
• Purity: Greater than 95% as determined by HPLC and SDS PAGE.
• Formulation: Sterile filtered and lyophilized from 0.6 mg/ml in PBS buffer.
• Solubility: Add 0.2 ml of deionized water and let the lyophilized pellet dissolve completely.
• Applications: ELISA, Western blotting, cell culture and/or animal studies.
• Storage: For long term, store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized APM-1 remains stable for 24 months when stored at -20°C.

Gene Information

• Gene Name: ADIPOQ adiponectin, C1Q and collagen domain containing [ Homo sapiens ]
• Synonyms: ADIPOQ; adiponectin, C1Q and collagen domain containing; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; adiponectin; APM1
• Gene ID: 9370
• mRNA Refseq: NM_004797
• Protein Refseq: NP_004788
• UniProt ID: Q15848
• Chromosome Location: 3q27
• MIM: 605441
• Pathway: Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus
• Function: cytokine activity; eukaryotic cell surface binding;hormone activity; protein homodimerization activity