Recombinant Mouse Adiponectin, Globular Domain

• Cat.No.: Adipoq-75M
• Product Overview: Recombinant mouse globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E.coli and purified by using conventional chromatography techniques, 16 kDa (138 aa).

Specification

• Species: Mouse
• Source: E.coli
• Tag: Non
• Protein Length: 111-247 a.a.
• Description: Adiponectin/Acrp30 (247amino acids) is adipocyte complement-related protein of 30kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice.
• Sequences of amino acids: MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITV YMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYA DNVNDSTFTG FLLYHDTN
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 5 mM DTT, 10% glycerol
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: Adipoq adiponectin, C1Q and collagen domain containing [ Mus musculus ]
• Synonyms: ACDC; ACRP30 ; ADIPQTL1; ADPN ; APM-1; APM1; AdipoQ;GBP28; adiponectin; apM-1; apM1; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; Gelatin-binding protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1Q and collagen domain-containing; adiponectin, C1Q and collagen domain containing; adipose most abundant gene transcript 1; gelatin-binding protein 28; APN; 30kDa; adipo; adipocyte complement related protein; gAcrp30
• Gene ID: 11450
• mRNA Refseq: NM_009605
• Protein Refseq: NP_033735
• UniProt ID: Q60994
• Chromosome Location: 16 16.0 cM
• Pathway: Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus
• Function: hormone activity; protein binding; receptor binding