Recombinant Human ACVR1B protein, GST/His-tagged

• Cat.No.: ACVR1B-231H
• Product Overview: Recombinant Human ACVR1B, transcript variant 1, fused with GST tag at N-terminal and His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&GST
• Description: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 84.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ACVR1B activin A receptor, type IB [ Homo sapiens ]
• Official Symbol: ACVR1B
• Synonyms: ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB
• Gene ID: 91
• mRNA Refseq: NM_004302
• Protein Refseq: NP_004293
• MIM: 601300
• UniProt ID: P36896