Active Recombinant Human ACVR1B protein, hFc-tagged

• Cat.No.: ACVR1B-529H
• Product Overview: Recombinant Human ACVR1B protein(NP_004293.1)(Met1-Glu126), fused with hFc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: Met1-Glu126
• Form: Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized human TDGF1-His at 10 μg/mL (100 μL/well) can bind ACVR1B-Fc, the EC50 of human ACVR1B-Fc is 3-20 ng/mL.
• Molecular Mass: The recombinant human ACVR1B consists of 341 amino acids and predicts a molecular mass of 38.1 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: ACVR1B activin A receptor, type IB [ Homo sapiens ]
• Official Symbol: ACVR1B
• Synonyms: ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB
• Gene ID: 91
• mRNA Refseq: NM_004302
• Protein Refseq: NP_004293
• MIM: 601300
• UniProt ID: P36896